Membrane Fluidity and Oxidative Stress in Patients with Periodontitis

Periodontitis leads to the destruction of dental tissue through polymicrobial interactions, inflammation, and increased oxidative stress. The aim this study was measure levels nitrates (NO3−), malondialdehyde (MDA), membranal fluidity (MF) in gingival subjects with or without periodontitis. A total 120 participants from Dentistry School University Guadalajara were investigated. approved by ethics committee our institution, registration number CI-01221. clinical parameters measured probing depth (PD), attachment level (CAL), bleeding on (BoP). NO3− using Greiss reaction, while MDA determined colorimetrically FR12 Kit (Oxford Biomedical Research). Membrane quotient Ie/Im according method Ortiz collaborators. Student t-test, Spearman correlation, chi-square are used calculate results. results showed higher PD, CAL, BoP patients. There a positive correlation between MF PD. Moreover, positively correlated PD CAL. Increases resulted NO3−, MDA, MF. Similarly, increases CAL We conclude that facilitated progression periodontitis